J investing allergol clin immunol impact factor 2011 calendar

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Kokubo1, H. Togashi3, K. Enomoto4, T. Enomoto5 1Food Research and Development Laboratory. Probiotic microorganisms have been shown to be effective in the treatment of allergic inflammation and food allergy, but their efficacy remains controversial. This study tested the effect of a yogurt supplemented with a probiotic strain Bifidobacterium longum BB in the treatment of Japanese cedar pollinosis JCPsis.

Forty subjects with a clinical history of JCPsis were given yoghurt either containing BB BB yoghurt or without BB placebo yoghurt at 2 g per day for 14 weeks, in a randomized, double-blind, placebocontrolled trial. Subjective symptoms and self-care measures were recorded daily and blood samples were taken before and during the intervention at weeks 4, 9, and 14 to measure the blood parameter levels related to JCPsis.

Yoghurt supplemented with BB significantly alleviated eye symptoms compared with placebo yoghurt odds ratio 0. Although no statistically significant differences were detected, nasal symptoms such as itching, rhinorrhea, and blockage, as well as throat symptoms tended to be relieved with the BB yoghurt. A decreased trend in the difference from baseline levels of JCP-specific IgE levels was also observed at week 4 in the BB group compared with the placebo group. PMID: Abstract Hypersensitivity pneumonitis is a dynamic and heterogeneous group of diseases resulting from inhalational exposure to a variety of organic and inorganic dusts.

In the United States, it has predominantly been considered an occupational disease, such as in farmer's lung, bagassosis, and in the plastics and paint industry with isocyanate exposure. In Japan, however, the most common exposure to antigen has been associated with the home environment.

All susceptible patient populations are at potential risk to develop this disease under appropriate antigen exposure. The clinical course can be acute, subacute, or chronic depending on the nature of the antigen and the circumstances under which exposure occurs.